How does Modafinil work Damian Alexander, MD discusses How does Modafinil work

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In this video I will discuss
How does Modafinil work

Currently, Modafinil is believed to work by
Increasing the sensitivity of the brain to excitatory neurotransmitters
Specifically noradrenaline-which is also known as norepinephrine
The effects of noradrenaline on the CNS (central nervous system) include
Increased attention,
memory, learning and cerebral plasticity
Noradrenaline stimulates the sympathetic branch of the nervous system
(The accelerator pedal of the CNS)
Noradrenaline increases blood glucose, mobilizes fatty acids from fat stores,
Increases heart rate, increases blood pressure and inhibits digestive processes
These effects lead to increased energy levels
While you would expect this to show more cardiovascular system side-effects
This does not happen in practice
Modafinil interacts with a large number of neurotransmitter systems
Yet it rarely interferes with other chemical balances in the body
And this is perhaps why it has a lower risk -and number- of potential side effects
Modafinil also works by restricting the parts of your brain that make you sluggish or sleepy
It does this by decreasing the sensitivity to inhibitory neurotransmitters like GABA
Modafinil is considered superior to
conventional stimulants
Because it doesn’t affect heart rate, blood pressure
And it does not raise anxiety, agitation
or promote insomnia
Modafinil is believed to lack the side effects of classic stimulants (amphetamins)
Due to the fact that it also influences
histamine levels
In the brain, histamine lowers susceptibility to convulsion, drug sensitization,
Denervation supersensitivity, ischemic lesions
and stress
Histamine is also involved in sleep regulation
And this is why Modafinil users can
sleep if they want to
Modafinil is the main metabolized element
from Adrafinil
And though both drugs have the
same desired result,


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